Indications:
This test measures a zonulin family protein (ZFP), identified as properdin. High serum levels of ZFP (antigen) are correlated with abnormal results of the Lactulose Mannitol test; the long-accepted standard for intestinal permeability.
Elevated levels of ZFP have been associated with metabolic syndrome, obesity, and several autoimmune, inflammatory and neoplastic diseases. Such diseases include Celiac disease, type I diabetes, juvenile non-alcoholic fatty liver disease, and evidence is accumulating for multiple sclerosis, rheumatoid arthritis, asthma and inflammatory bowel disease.
Elevated serum levels of ZFP and increased permeability are commonly observed in patients at risk of developing Crohn’s disease and type 1 diabetes patients, prior to the onset of symptoms.
Test ID: ZONS
Turnaround time: 8 days
Sample Collection Instructions: Standard venepuncture procedure
Sample Requirements: Yellow (SST)
Sample Stability: Postal acceptable
Sample Report: rep-zonulin-serum.pdf