Normal metabolism of methionine is critical for cellular methylation of DNA, proteins and neurotransmitters. Aberrant methionine metabolism can occur in anyone at any age and can be associated with numerous health consequences including cardiovascular disease and cancer. The Methylation Profile provides a functional assessment of the phenotypic expression of common SNPs (MTHFR, MS, CBS) by evaluating the plasma levels of methionine, cysteine, SAM, SAH, homocysteine, adenose and cystathionine. It also provides the important “methylation index”, a ratio of SAM to SAH.
The blood sample for this profile must be centrifuged and the plasma separated and frozen promptly after collection (a kit is provided with full instructions and all necessary materials). Once the sample has been frozen it remains stable at ambient temperature and is suitable for next-day return to Viva Health Laboratories.
Sample report: Methylation Profile report
Test datasheet: Methylation Profile Resource
Instructions: Sample collection instructions